Studies on Medicago lupulina saponins. 6. Some chemical characteristics and biological activity of root saponins

Wiesław Oleszek, Marian Jurzysta, Piotr Górecki, Stanisław Burda, Michał Płoszyński

Abstract


The saponin fraction of black medic trefoil (Medicago lupulina) roots was isolated and purified. Its hydrolysis afforded several aglycones that have been identified by spectral and chemical properties as medicagenic acid, hederagenine and soyasapogenols: B, C, D, E and F. They made up, respectively. 46.9 and 45% of total sapogenins isolated. Two-dimensional TLC of M. lupulina root saponins revealed fourteen compounds, two of which were medicagenic acid glycosides. The haemolytic, antifungal and allelopathic activities of M. lupulina and M. media roots are compared and discussed.

Keywords


Medicago lupulina roots; saponins; isolation; biological activity

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DOI: https://doi.org/10.5586/asbp.1987.013

Journal ISSN:
  • 2083-9480 (online)
  • 0001-6977 (print; ceased since 2016)
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Publisher
Polish Botanical Society